Isabel is a little girl from Oaxaca, Mexico who loves everything to do with science. Living with her father and brother in a remote house high upon a cliff, she spends days learning about the wonders of the nature and night after night dreaming of the world laid out in her books. After a terrifying dream that is infiltrated by beastly wild tigers, Isabel vows never to sleep again. Soon, the whole family has caught Isabel’s insomnia and life will never be the same.